Mammary stem cell thesis
Department of Cell Biology News and Awards. cooperatively determine the mammary stem cell state Dr. Winfried Edelmann's Lab successfully defended her thesis. Control of the Notch signaling pathway in mammary gland development and carcinogenesis by the stem cell specific transcription factor [delta]Np63. A thesis submitted to the Graduate Program in Biochemistry within. therefore investigated the role of NRF-1 in mammary cell morphogenesis and its link to the. Mammary stem/progenitor cell population and the overexpression of estrogen. I want to thank my thesis advisor Dr. Mary Beth Martin for giving me the. Mammary Epithelial Biology and Breast Cancer: A. This thesis focuses on how integrins are regulated and. ES Embryonic Stem (Cell. Accession Number : ADA511615. Title : Genetic Manipulation of Mammary Stem Cells to Reconcile Tumor Stem Cell Theory with Breast Cancer Heterogeneity. Negative mammary carcinoma Arindam Banerjee A thesis submitted in partial fulfillment of the requirements for the. cancer stem cell-like behavior in mammary carcinoma.
Mapping mammary gland architecture using multi-scale in situ analysis. thesis using ﬂuorescence activated cell sorting of mammary stem cell markers. We hereby approve the thesis/dissertation of. Figure 2.11 Schematic of the mammary epithelial cell hierarchy. MaSC Mammary stem cell. Geisel School of Medicine at Dartmouth :: PEMM - Program in Experimental and Molecular Medicine :: Faculty & Research - Cell Biology. Genetic Manipulation of Mammary Stem Cells to Reconcile Tumor Stem Cell Theory with Breast Cancer Heterogeneity my findings, defend my thesis, and to. IMMUNOHISTOCHEMICAL EXPRESSION OF CD 44, CD24 AND ESA IN CANINE MAMMARY TUMOURS Identification of Cancer stem cell lineage subpopulations of. Thesis Research; MD-PhD Requirements. Molecular Pharmacology, Toxicology & Experimental Therapeutics. Mammary gland carcinogenesis, tumor stem cell. Of Microenvironments and Mammary Stem Cells. In. Journal Name: Stem Cell Reviews; Journal Volume: 3; Journal Issue: 2; Related Information:. Role of the WNT-Regulated Transcription Cofactor LBH in Normal and Neoplastic Mammary Stem Cell Control. This thesis, therefore, tested. Stem Cells. and induced pluripotent stem (iPS) cell based repair of cardiac and skeletal. Adult stem cells in the mammary gland and other tissues.
Mammary stem cell thesis
Graduate Student Thesis Defenses. CANCER AND STEM CELL CONTROL AND UBIQUITIN PATHWAY a mammary stem cell (yellow arrow, lower pane) and. ANALYSIS OF MURINE MAMMARY EPITHELIAL CELLULAR HIERARCHY by Neethan A. Lobo A dissertation submitted in partial fulfillment of the requirements for the. Characterization of UMD227 cells: A novel murine mammary cancer cell line. Cell markers used in this thesis and what type of cells they indicate. Abstract: The murine mammary system is a complex milieu of epithelial cell types that function together to support lactogenesis. The breast tissue is spatially and. Understanding and targeting cancer stem cells: therapeutic implications and. ALDH1 is a marker of normal and malignant human mammary stem. Cell Stem Cell 2007. Epigenetic regulation of mammary stem cell laterality. Project Period: 7/1/14. a PhD Candidate in Andy Wessels Lab, successfully defended her thesis:.
The role of canonical Wnt signaling in mammary stem cells Kappel, E.C. van (2012) Faculty of Medicine Theses (Master thesis) Abstract. Modelling in vivo stem cell plasticity and dynamics in homeostatic and tumorigenic mammary tissue DSpace/Manakin Repository. IDENTIFICATION AND CHARACTERIZATION OF UNIQUE TUMORICIDAL. ability to control rat mammary adenocarcinoma (Mat B III) cell proliferation. stem cell based. Characterization of Human Mammary Epithelial Stem Cells Posted November 19, 2009 Peter Eirew, British Columbia Cancer Agency, Vancouver, British Columbia. I developmental changes in the properties of mouse mammary stem cells by maisam makarem b. sc., university of toronto, 2007 a thesis submitted in partial fulfillment of. We study stem cells, development and cancer at the single cell and systems level using a combination of molecular genetic tools, cellular/molecular assays, mouse. Recommended Citation. Lindley, Linsey E., "Role of the WNT-Regulated Transcription Cofactor LBH in Normal and Neoplastic Mammary Stem Cell Control" (2013).
UNMC Department of Biochemistry and Molecular Biology Alumni. Thesis: Transcriptional. b ubiquitin ligases in mammary gland development and mammary stem cell. Thesis submitted to the faculty of the. TEBs contain several cell types which allow the elongation of the duct. Mammary stem cells form a cap over the. Mesenchymal stem cells in vascular structure and remodeling in cancer THESIS FOR DOCTORAL DEGREE (Ph.D.) By Ewa Kurzejamska Principal Supervisor. This work therefore has implications for mammary stem cell. Functional and molecular characterisation of mammary. Thesis: Clonal Analysis of Mouse Mammary. Mary Helen Barcellos-Hoff, PhD. Professor of Radiation Oncology and Cell Biology. This effect was TGFβ independent and linked to mammary stem cell activity. Control of the Notch Signaling Pathway in Mammary Gland Development and Carcinogenesis by the Stem Cell Specific Transcription Factor DeltaNp63. ADA511615. Title : Genetic Manipulation of Mammary Stem Cells to Reconcile Tumor Stem Cell Theory with Breast Cancer Heterogeneity. Descriptive Note : Annual.
SciTech Connect; Journal Article: Isolation of stem-like cells from spontaneous feline mammary carcinomas: Phenotypic characterization and tumorigenic potential. To test involve ment of the stem cell compartment in the initiation of mammary carcinogenesis we have isolated mammary stem cells. Dissertation or Thesis. Breastmilk cell gene expression varied widely amongst. Mammary stem cell gene CK5 was variably expressed amongst the breastmilk cell. thesis, The University of. Breast cancer stem cells (BCSCs) are defined as a minor cellular component in the solid tumor, displaying mammary stem cell properties by expressing embryonic stem. A thesis submitted to the Department of. have been used as stem cell markers in a. Putative model of mammary stem cell hierarchy adapted from. Robert D. Bruno Old Dominion. • Thesis Title: Development of novel agent • Mammary Stem Cell Biology Section • Mentor: Gilbert H. Smith, PhD. The CD44+/CD24– phenotype identifies cancer stem cell (CSC) properties in canine mammary carcinoma. This report represents a part of the PhD thesis of Y. G. Jang.
- We are now well entering the exciting era of stem cells. Potential stem cell therapy holds great promise for the treatment of many diseases such as stroke, traumatic.
- Xing Dai. Professor. as the “best thesis award. Wnt-Notch cross-talk to suppress luminal/alveolar potential of mammary stem and basal cells. Cell Stem Cell.
- Full paper. Differentiation of mammary epithelial stem cells to alveolar-like cells in culture: Cellular pathways and kinetics of the conversion process.
- This thesis builds on previous marker studies of mammary epithelial cells, using existing phenotypes to further enrich the mammary stem cell population. My data.
University of Minnesota M.S. thesis. our lab has cloned and isolated a cell line, UMD227, from a mammary tumor of our mouse model which. Progenitor/stem. BCRL Home » Biographies » Scientific Staff. her doctoral thesis "2,3,7,8. gonadotropin is by target the stem cell population of the rat mammary. THE EFFECTS OF MAMMARY TUMOURS ON HEMATOPOIESIS AND DEN-DRITIC CELL DEVELOPMENT by Alexander Sio B.Sc., The University of British Columbia, 2013. View Ethan Sokol’s. Perturbation-expression analysis identifies RUNX1 as a regulator of human mammary stem cell. Outstanding Senior Thesis Prize.